publications

Lab member names are underscored
*Corresponding author(s)
#Equal contributions

  1. Chen J, Chen M, Zhu TF*. Translating protein enzymes without aminoacyl-tRNA synthetases. Chem, 7:786-798, (2021). [PDF]
  2. Ling JJ#, Fan C#, Qin H, Wang M, Chen J, Wittung-Stafshede P, Zhu TF*. Mirror-image 5S ribonucleoprotein complexes. Angewandte Chemie International Edition, 59:3724-3731, (2020). [PDF]
  3. Qin N#,*, Liang P#, Wu C#, Wang G, Xu Q, Xiong X, Wang T, Zolfo M, Segata N, Qin H, Knight R, Gilbert JA*, Zhu TF*. Longitudinal survey of microbiome associated with particulate matter in a megacity. Genome Biology, 21:55, (2020). [PDF]
  4. Zhang B#, Deng Q#, Zuo C, Yan B, Zuo C, Cao XX, Zhu TF, Zheng JS*, Liu L*. Ligation of soluble but unreactive peptide segments in the chemical synthesis of Haemophilus Influenzae DNA ligase. Angewandte Chemie International Edition, 58:12231-12237, (2019). [PDF]
  5. Wang M#, Jiang W#, Liu X#, Wang J#, Zhang B, Fan C, Liu L, Pena-Alcantara G, Ling J, Chen J, Zhu TF*. Mirror-image gene transcription and reverse transcription. Chem, 5:848-857, (2019). [PDF]
  6. Liu X, Zhu TF*. Sequencing mirror-image DNA chemically. Cell Chemical Biology, 25:1151-1156, (2018). [PDF]
  7. Wang G#, Du M#, Wang J*, Zhu TF*. Genetic variation may confound analysis of CRISPR-Cas9 off-target mutations. Cell Discovery, 4:18, (2018). [PDF]
  8. Kayani MU#, Doyle SM#, Sangwan N, Wang G, Gilbert JA*, Christner BC*, Zhu TF*. Metagenomic analysis of basal ice from an Alaskan glacier. Microbiome, 6:123, (2018). [PDF]
  9. Jiang W#, Zhang B#, Fan C#, Wang M#, Wang J, Deng Q, Liu X, Chen J, Zheng J, Liu L*, Zhu TF*. Mirror-image polymerase chain reaction. Cell Discovery, 3:17037, (2017). [PDF]
  10. Pontefract A, Zhu TF, Walker VK, Hepburn H, Lui C, Zuber MT, Ruvkun G, Carr CE*. Microbial diversity in a hypersaline sulfate lake: a terrestrial analog of ancient Mars. Frontiers in Microbiology, 8:1819, (2017). [PDF]
  11. Xu W#, Jiang W#, Wang J#, Yu L#, Chen J, Liu X, Liu L*, Zhu TF*. Total chemical synthesis of a thermostable enzyme capable of polymerase chain reaction. Cell Discovery, 3:17008, (2017). [PDF]
  12. Su HW#, Zhu JH#, Li H, Cai RJ, Ealand C, Wang X, Chen YX, Kayani MU, Zhu TF, Moradigaravand D, Huang H, Kana BD, Javid B*. The essential mycobacterial amidotransferase GatCAB is a modulator of specific translational fidelity. Nature Microbiology, 1:16147, (2016). [PDF]
  13. Wang Z#, Xu W#, Liu L*, Zhu TF*. A synthetic molecular system capable of mirror-image genetic replication and transcription. Nature Chemistry, 8(7):698-704, (2016). (Highlighted by Nature [PDF], Scientific American, C&EN, and F1000Prime) [PDF]
  14. Jiang W*, Zhu TF*. Targeted isolation and cloning of 100-kb microbial genomic sequences by Cas9-assisted targeting of chromosome segments. Nature Protocols, 11(5):960-975, (2016). [PDF]
  15. Jiang W, Zhao X, Gabrieli T, Lou C*, Ebenstein Y*, Zhu TF*. Cas9-Assisted Targeting of CHromosome segments CATCH enables one-step targeted cloning of large gene clusters. Nature Communications, 6:8101, (2015). [PDF]
  16. Zheng Y#, Kayani MU#, Zhu TF*. Rapid identification of multi-strain HBV infection in patient by high-throughput DNA sequencing. Quantitative Biology, 3(2):103-106, (2015). [PDF]
  17. Jiang W, Liang P, Wang B, Fang J, Lang J, Tian G, Jiang J, Zhu TF*. Optimized DNA extraction and metagenomic sequencing of airborne microbial communities. Nature Protocols, 10(5):768-779, (2015). [PDF]
  18. Cao C, Jiang W#, Wang B#, Fang J, Lang J, Tian G*, Jiang J*, Zhu TF*. Inhalable microorganisms in Beijing's PM2.5 and PM10 pollutants during a severe smog event. Environmental Science & Technology, 48(3):1499-1507, (2014). (Web of Science 'Highly Cited Paper': top 1% of the field; Highlighted by Nature, Scientific American, Popular Science, The Scientist, Los Angeles Times, and Business Insider) [PDF]
  19. Zhu TF, Budin I, Szostak JW*. Preparation of fatty acid micelles. Methods in Enzymology, 533:283-288, (2013). [PDF]
  20. Zhu TF, Budin I, Szostak JW*. Vesicle extrusion through polycarbonate track-etched membranes using a hand-held mini-extruder. Methods in Enzymology, 533:275-282, (2013). [PDF]
  21. Zhu TF, Budin I, Szostak JW*. Preparation of fatty acid or phospholipid vesicles by thin-film rehydration. Methods in Enzymology, 533:267-274, (2013). [PDF]
  22. Zhu TF, Adamala K, Zhang, N, Szostak JW*. Photochemically driven redox chemistry induces protocell membrane pearling and division. Proceedings of the National Academy of Sciences USA, 109(25):9828-9832, (2012). [PDF]
  23. Zhu TF, Szostak JW*. Exploding vesicles. Journal of Systems Chemistry, 2:4, (2011). [PDF]
  24. Schrum J, Zhu TF, Szostak JW*. The origins of cellular life. Cold Spring Harbor Perspectives in Biology, 2(9):a002212, (2010). [PDF]
  25. Zhu TF, Szostak JW*. Coupled growth and division of model protocell membranes. Journal of the American Chemical Society, 131: 5705-5713, (2009). (Highlighted by PBS NOVA, BBC, Discovery Science Channel, National Geographic Channel, C&EN, HHMI Bulletin, and Scientific American) [PDF]
  26. Zhu TF, Szostak JW*. Preparation of large monodisperse vesicles. PLOS ONE, 4(4):e5009, (2009). [PDF]
  27. Zhu T, Zhao HC, Wu J, Hoylaerts MF*. Three-dimensional reconstruction of thrombus formation during photochemically induced arterial and venous thrombosis. Annals of Biomedical Engineering, 31:515-525, (2003). (Cover story) [PDF]
  28. Zhao HC*, Zhu T, Wu J, Xi BS. Effect of simulated microgravity on aged pea seed vigour and related physiological properties. Colloids and Surfaces B: Biointerfaces, 27:311-314, (2003). [PDF]
  29. Zhao HC*, Zhu T, Wu J, Xi BS. Effect of Ca2+ on H+-ATPase activity of plasma membrane in wheat root. Colloids and Surfaces B: Biointerfaces, 28:147-152, (2003). [PDF]
  30. Zhao HC*, Wu J, Zheng L, Zhu T, Xi BS. Effect of sound stimulation on Dendranthema morifolium callus growth. Colloids and Surfaces B: Biointerfaces, 29:143-147, (2003). [PDF]
  31. Zhao HC*, Zhu T, Wu J, Xi BS. Role of protein kinase in the effect of sound stimulation on the PM H+-ATPase activity of Chrysanthemum callus. Colloids and Surfaces B: Biointerfaces, 26:335-340, (2002). [PDF]